Evaluation of sow seroconversion with the use of inoculum at different doses and vehicles against porcine epidemic diarrhea

Authors

  • Nancy Paulina García Cano Rubí Universidad Nacional Autónoma de México. Facultad de Medicina Veterinaria y Zootecnia. Ciudad Universitaria, Av. Universidad #3000, Colonia, C.U., Coyoacán, 04510 Ciudad de México, México. https://orcid.org/0000-0002-5101-6729
  • Francisco Ernesto Martínez-Castañeda Universidad Autónoma del Estado de México. Instituto de Ciencias Agropecuarias y Rurales. México. https://orcid.org/0000-0003-0168-921X
  • Elein Hernández Trujillo Universidad Nacional Autónoma de México. Facultad de Estudios Superiores Cuautitlán. México. https://orcid.org/0000-0002-8761-3656
  • Rosa Elena Sarmiento Silva Universidad Nacional Autónoma de México. Facultad de Medicina Veterinaria y Zootecnia. Ciudad Universitaria, Av. Universidad #3000, Colonia, C.U., Coyoacán, 04510 Ciudad de México, México. https://orcid.org/0000-0001-7430-5657
  • Rolando Beltrán Figueroa Universidad Nacional Autónoma de México. Facultad de Medicina Veterinaria y Zootecnia. Ciudad Universitaria, Av. Universidad #3000, Colonia, C.U., Coyoacán, 04510 Ciudad de México, México. https://orcid.org/0000-0001-7369-7329
  • Montserrat Elemi García-Hernández Universidad Nacional Autónoma de México. Facultad de Medicina Veterinaria y Zootecnia. https://orcid.org/0000-0001-6205-4176
  • María Elena Trujillo-Ortega Universidad Nacional Autónoma de México. Facultad de Medicina Veterinaria y Zootecnia. Ciudad Universitaria, Av. Universidad #3000, Colonia, C.U., Coyoacán, 04510 Ciudad de México, México. https://orcid.org/0000-0002-7229-260X

DOI:

https://doi.org/10.22319/rmcp.v14i2.6146

Keywords:

Inoculum, Porcine Epidemic Diarrhea, Seroconversion

Abstract

Porcine epidemic diarrhea (PED) is a highly contagious enteric disease of pigs, which has caused great economic losses to the swine industry worldwide. The known measure for PED control prior to the development and launch of vaccines in 2017 in Mexico, was "feedback" or "liquefaction". It was a widely used measure during the PED outbreak in 2013; however, there is no homogeneity in its use among the various authors who recommend it. Currently, several studies have experimented with other types of prophylaxis, such as oral immunization with PED virus obtained from cell culture isolation, which allows quantification of the infectious virus and ensures that only the virus, and no other agent, is being used as inoculum. The objective of the present study was to compare the time of seroconversion in sows inoculated with the quantified virus with four different vehicles (milk, wheat, direct, and water) and different doses of vehicle (1 ml, 2 ml, and 3 ml) at different pregnancy stages and with a different number of farrowings. The study was conducted at CEIEPP, a full-cycle farm with 170 females. The present study showed that the vehicles with the best results were the inoculum with water and the direct inoculum combined with the 1 ml dose, as the combination of these vehicles and an inoculum dose resulted in seroconversion in more than 90 % of the sows from the second week post inoculation.

Downloads

Download data is not yet available.

References

Wang XY, Ji CJ, Zhang X, Xu DP, Zhang DL. Infection, genetic and virulence characteristics of porcine epidemic diarrhea virus in northwest China. Infect Genet Evol 2018;62:34-39. https://doi.org/10.1016/j.meegid.2018.04.001.

Díaz I, Pujols J, Cano E, Cuadrado R, Navarro N, Mateu E, et al. Assessment of three commercial ELISAs for the detection of antibodies against Porcine epidemic diarrhea virus at different stages of the immune response. Vet Immunol Immunopathol 2021;234:110206. https://doi.org/10.1016/j.vetimm.2021.110206.

Li Z, Ma Z, Li Y, Gao S. Virus de la diarrea epidémica porcina: mecanismos moleculares de atenuación y vacunas. Microb Pathog 2020;149:104553. https://doi.org/10.1016/j.micpath.2020.104553.

Yang S, Li Y, Wang B, Yang N, Huang X, Chen Q, et al. Acute porcine epidemic diarrhea virus infection reshapes the intestinal microbiota. Virology 2020;548:200-212. https://doi.org/10.1016/j.virol.2020.07.001.

Antas M, Woźniakowski G. Current status of porcine epidemic diarrhoea (PED) in European pigs. J Vet Res 2019;63(4):465–470.

Chen P, Wang K, Hou Y, Li H, Li X, Yu L, et al. Genetic evolution analysis and pathogenicity assessment of porcine epidemic diarrhea virus strains circulating in part of China during 2011–2017. Infect Genet Evol 2019;69:153–165.

Li HJ, Gao DS, Li YT, Wang YS, Liu HY, Zhao J. Antiviral effect of lithium chloride on porcine epidemic diarrhea virus in vitro. Res Vet Sci 2018;118:288–294.

Gonzalo MB, Cáceres GG, Muñoz HB, Romero GL. Situación mundial de las nuevas cepas de la diarrea epidémica porcina. Albéitar publicación Vet Indep 2016;(193):24–26.

Weng L, Weersink A, Poljak Z, Lange K De, Massow M. An economic evaluation of intervention strategies for Porcine Epidemic Diarrhea (PED). Prev Vet Med 2016;134:58–68. http://dx.doi.org/10.1016/j.prevetmed.2016.09.018.

Zentkovich MM, Nelson SW, Stull JW, Nolting JM, Bowman AS. Inactivation of porcine epidemic diarrhea virus using heated water. Vet Anim Sci 2016;2:1–3.

Paarlberg PL. Updated estimated economic welfare impacts of porcine epidemic diarrhea virus ( PEDV) 2014:1–38.

Rogers-Montoya NA, Martínez-Castañeda FE, Trujillo-Ortega ME. Costo y efecto del virus de la Diarrera Epidémica Porcina en el desempeño reproductivo de una granja de ciclo completo en México. ITEA. 2022. https://doi.org/10.12706/itea.2021.034.

Amador-Cruz, J, Martínez-Castañeda FE, Trujillo-Ortega ME. Impacto económico de la Diarrea Epidémica Porcina en México [en prensa]. Agroproductividad 2022.

Goede D, Morrison RB. Production impact y time to stability in sow herds infected with porcine epidemic diarrhea virus (PEDV). Prev Vet Med 2016;123:202–207.

Lee C. Porcine epidemic diarrhea virus: An emerging and re-emerging epizootic swine virus. Virol J 2015;12(1):1–16. http://dx.doi.org/10.1186/s12985-015-0421-2.

ZOETIS. Otorga Zoetis licencia condicional para vacuna contra la Diarrea Epidémica Porcina 2014: https://www.zoetis.mx/news-and-media/index.aspx.

Park JE, Shin HJ. Porcine epidemic diarrhea vaccine efficacy evaluation by vaccination timing and frequencies. Vaccine 2018;36(20):2760–2763. https://doi.org/10.1016/j.vaccine.2018.03.041.

Trujillo-Ortega ME, Beltrán-Figueroa R, García-Hernández ME, et al. Isolation and characterization of porcine epidemic diarrhea virus associated with the 2014 disease outbreak in Mexico: case report. BMC Vet Res 2016;12(1):132. doi:10.1186/s12917-016-0763-z.

Becerra HJF. Aislamiento del virus de la diarrea epidémica porcina en cultivo celular. [tesis Licenciatura]. Universidad Nacional Autónoma de México, México. 2016. https://repositorio.unam.mx/contenidos/296209.

Clement T, Singrey A, Lawson S, Okda F, Nelson J, Diel D, et al. Measurement of neutralizing antibodies against porcine epidemic diarrhea virus in sow serum, colostrum, and milk samples and in piglet serum samples after feedback. J Swine Heal Prod 2016;24(3):147–153.

Diel DG, Lawson S, Okda F, Singrey A, Clement T, Fernandes MHV, et al. Porcine epidemic diarrhea virus: An overview of current virological and serological diagnostic methods. Virus Res 2016;226:60–70.

Ouyang K, Shyu DL, Dhakal S, Hiremath J, Binjawadagi B, Lakshmanappa YS, et al. Evaluation of humoral immune status in porcine epidemic diarrhea virus (PEDV) infected sows under field conditions. Vet Res 2015;46:140.

Jung K, Saif LJ. Porcine epidemic diarrhea virus infection: etiology, epidemiology, pathogenesis and immunoprophylaxis. Vet J 2015;204(2):134–143.

Langel SN, Wang Q, Vlasova AN, Saif LJ. Host factors affecting generation of immunity against porcine epidemic diarrhea virus in pregnant and lactating swine and passive protection of neonates. Pathogens 2020;9:130.

Langel SN, Paim FC, Alhamo MA, Buckley A, Van Geelen A, Lager KM, Vlasova AN, Saif LJ. Stage of gestation at porcine epidemic diarrhea virus infection of pregnant swine impacts maternal immunity and lactogenic immune protection of neonatal suckling piglets. Frontierns in Immunology 2019;10:727.

Gillespie T, Song Q, Inskeep M, Stone S, Murtaugh MP. Effect of booster vaccination with inactivated porcine epidemic diarrhea virus on neutralizing antibody response in mammary secretions. Viral Immunology 2018;31(1):62–68.

Jung K, Saif L, Wang Q. Porcine epidemic diarrhea virus (PEDV): An update on etiology, transmission, pathogenesis, and prevention and control. Virus Research 2020; 286:198045.

Published

2023-04-03

How to Cite

García Cano Rubí, N. P., Martínez-Castañeda, F. E., Hernández Trujillo, E., Sarmiento Silva, R. E., Beltrán Figueroa, R., García-Hernández, M. E., & Trujillo-Ortega, M. E. (2023). Evaluation of sow seroconversion with the use of inoculum at different doses and vehicles against porcine epidemic diarrhea. Revista Mexicana De Ciencias Pecuarias, 14(2), 466–475. https://doi.org/10.22319/rmcp.v14i2.6146
Metrics
Views/Downloads
  • Abstract
    941
  • PDF (Español)
    248
  • PDF
    253
  • Texto completo (Español)
    409

Issue

Section

Research Notes

Metrics

Similar Articles

1 2 3 4 5 6 7 8 > >> 

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)