Relationships among ß-hydroxybutyrate, calcium and non-esterified fatty acids in blood with milk yield losses at early lactation

Autores/as

  • Rufino López-Ordaz Universidad Autónoma Chapingo. Posgrado en Producción Animal. Carr. México-Texcoco. 56230. Chapingo, Estado de México. México.
  • Gabriela Pérez-Hernández Universidad Autónoma Chapingo. Posgrado en Producción Animal. Carr. México-Texcoco. 56230. Chapingo, Estado de México. México.
  • Hugo Alonso Ramírez-Ramírez Iowa State University. Animal Science Department. Ames, IA.USA.
  • Reyes López-Ordaz Universidad Autónoma Metropolitana. Departamento de Producción Agrícola. Ciudad de México, México.
  • Germán David Mendoza-Martínez Universidad Autónoma Metropolitana. Departamento de Producción Agrícola. Ciudad de México, México.
  • Agustín Ruíz-Flores Universidad Autónoma Chapingo. Posgrado en Producción Animal. Carr. México-Texcoco. 56230. Chapingo, Estado de México. México.

DOI:

https://doi.org/10.22319/rmcp.v12i1.5105

Palabras clave:

Negative energy balance, Biomarkers, Metabolites, Milk yield, Metabolic dysfunctions

Resumen

The objectives were to study the associations of concentrations of β-hydroxybutyrate acid (BHBA), calcium (Ca2+), and non-esterified fatty acids (NEFA) in blood serum 7 d prepartum with losses in milk yield (MY) and metabolic dysfunctions at seven and 14 d of lactation. Three hundred and thirty-six (336) Holstein-Friesian (780 ± 36 kg BW; which had lactated more than twice) were sampled by coccygeal venipuncture, 7 d before, and 7 and 14 d after parturition. For each sample and metabolite serum concentrations were stratified in thresholds and related to MY. When BHBA levels were high 7 d before parturition and were related to MY at d-7 postpartum, it was observed that 11.00 % of the cows lost 0.370 kg d-1 of milk. In contrast, no relationship was observed between BHBA prepartum and MY on d-14 of lactation. It was not observed any association between high NEFA and low Ca2+ levels prepartum and MY. NEFA concentrations ≥ 0.5 mmol L-1 on d-7 before calving were 7.6 more susceptible for lameness incidence (P≤ 0.01), and when BHBA ≥ 0.8 mmol L-1 cows were 2.4 times more likely to develop ketosis (P≤0.05) in the first 60 d in milk. In brief, data indicate that a high proportion of cows are above the thresholds of β-hydroxybutyrate and non-esterified fatty acids, and are also deficient in calcium, when determined one week before parturition. The risk thresholds for each metabolite were not associated with the amount of milk lost at d-14 after calving.

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Biografía del autor/a

Rufino López-Ordaz, Universidad Autónoma Chapingo. Posgrado en Producción Animal. Carr. México-Texcoco. 56230. Chapingo, Estado de México. México.

Profesor Investigador. Departamento de Zootecnia.

Gabriela Pérez-Hernández, Universidad Autónoma Chapingo. Posgrado en Producción Animal. Carr. México-Texcoco. 56230. Chapingo, Estado de México. México.

Estudiante de Maestría en Ciencis en Innovación Ganadera.

Hugo Alonso Ramírez-Ramírez, Iowa State University. Animal Science Department. Ames, IA.USA.

Professor

Reyes López-Ordaz, Universidad Autónoma Metropolitana. Departamento de Producción Agrícola. Ciudad de México, México.

Profesor investigador de tiempo completo

Germán David Mendoza-Martínez, Universidad Autónoma Metropolitana. Departamento de Producción Agrícola. Ciudad de México, México.

Proesor

Agustín Ruíz-Flores, Universidad Autónoma Chapingo. Posgrado en Producción Animal. Carr. México-Texcoco. 56230. Chapingo, Estado de México. México.

Profesor

Citas

Gross J, van Dorland HA, Bruckmaier RM, Schwarz FJ. Performance a metabolic profile energy balance with subsequent re-alimentation. J Dairy Sci 2011;94:1820–1830, doi: 10.3168/jds.2010-3707.

Veech RL, Chance B, Kashiwaya Y, Lardy HA, Cahill GF. Ketone bodies, potential therapeutic uses. Inter Union Biochem Mol Biol 2001;51:241-247, doi:10.1080/152165401753311780.

Ruderman NB, Goodman MN. Regulation of ketone body metabolism in skeletal muscle. Amer J Phys 1973;224:1391-1397. doi: 10.1152/ajplegacy.1973.224.6.1391.4.

Ospina PA, Nydam DV, Stokol T, Overton, TR. Associations of elevated non-esterified fatty acids and β-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the northeastern of Unites States. J Dairy Sci 2010;93:1596–1603. doi:10.3168/jds.2009-2852.

Schlumbohm C, Harmeyer J. Hyperketonemia impairs glucose metabolism in pregnant and nonpregnant ewes. J Dairy Sci 2004;87:350-358. doi:10.3168/jds.S0022-0302(04)73174-4.

Duffield T, Lissemore K, McBride M, Leslie K. Impact of hyperketonemia in early lactation dairy cows on health and production. J Dairy Sci 2009;92:571-580. doi: 10.3168/jds.2008-1507.

Horst RL, Goff JP, Reinhardt TA. Calcium and vitamin D metabolism in the dairy cow. J Dairy Sci 1994;77:1936–1951. doi: 10.3168/jds.S0022-0302(94)77140X.

Seifi HA, LeBlanc SJ, Leslie KE, Duffield TF. Metabolic predictors of postpartum disease and culling risk in dairy cattle. Vet J 2011; 188:216220. doi: 10.1016/j.tvjl.2010.04.007.

Chapinal N, LeBlanc S, Carson M, Leslie K, Godden S, Capel M, Duffield T. Herd-level association of serum metabolites in the transition period with disease, milk production, and early-lactation reproductive performance. J Dairy Sci 2012;95:1301-1309. doi:10.3168/jds.2011-4724.

García E. Modificaciones al sistema de clasificación climática de Köppen. Instituto de Geografía. 5ta. ed. México: UNAM; 2005.

Fox N, Hunn A, Mathers N. Sampling and sample size calculation. The National Institute for Health Research. USA: NHR RDs eM/YH; 2009.

NRC. Nutrient Requirements of Dairy Cattle. 7th revised ed. National Academy of Sciences, Washington, DC USA: National Academy Press; 2001.

Perkin Elmer. Perkin Elmer Corporation. Analytical methods for atomic absorption. Associations of Official Analytical chemists. 2000. Norwalk, Connecticut; 1996.

LeBlanc SJ, Duffield TF, Leslie KE, Bateman KG, Ten-Hag J, Walton JS, Johnson WH. The effect of prepartum injection of vitamin E on health in transition dairy cows. J Dairy Sci 2002;85:1416–1426. doi: 10.3168/jds.S0022-0302(02)74209-4.

SAS. SAS User’s Guide: Statistics (Version 9.1.3). SAS Inst. Inc. Cary, NC, USA; 2012.

López-Ordaz R, Tinajero, PT, López OR, Mendoza G, Roldan MJ, Vite A, Ruiz FA. Relaciones entre calcio, ácidos grasos no esterificados, e insulina sanguínea en preparto y leche bovina perdida en el inicio de la lactancia. Nova Scientia 2017;9(19):306-328. doi:10.21640/ns.v9i19.1053.

Raboisson D, Mounie M, Maigne M. Disease, reproductive performance, and changes in milk production associated with subclinical ketosis in dairy cows: A meta-analysis and review. J Dairy Sci 2015;97:7457–7563. doi: 10.3168/jds.2014-8237.

Bruckmaier RM, Gross JJ. Lactational changes in transition dairy cows. Anim Prod Sci 2017; 57:1471-1483. doi.org/10.1071/ANI1657.

Ospina PA, Nydam DV, Stokol T, Overton TR. Association between the proportions of sampled transition cows with increased nonesterified fatty acids and betahydroxybutyrate and disease incidence, pregnancy rate, and milk production at the herd level. J Dairy Sci 2010;93:3595–3601. doi: 10.3168/jds.2010-3074.

Kelly JM. Changes in serum B hydroxybutyrate concentrations in dairy cows kept under commercial farm conditions. Vet Rec 1977;101:499–502.

Suthar VS, Canelas-Raposo J, Deniz A, Heuwieser W. Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. J Dairy Sci 2013;96:2925–2938. doi: 10.3168/jds.2012-6035.

Mori M, Rossi S, Bonferoni MC, Ferrari F, Giuseppina S, Riva F, Del Fant C, Perotti C, Caramella C. Calcium alginate particles for the combined delivery of platelet lysate and vancomycin hydrochloride in chronic skin ulcers. Int J Pharmac 2014;461:505-513. doi.org/10.1016/j.ijpharm.2013.12.020.

van´t Klooster AT. Adaptation of calcium absorption from the small intestine of dairy cows’ changes in the dietary calcium intake and at the onset of lactation. Zeitschrift fuer Thierphysiology 1976;37:169-182.

Duffield TF, Lissemore KD, McBride BW, Leslie KE. Impact of hyperketonemia in early lactation dairy cow on health and production. J Dairy Sci 2005;92:571–580. doi:10.3168/jds.2008-1507.

Venjakob PL, Paiper L, Heuwieser W, Borchardt S. Association of postpartum hypocalcemia with early-lactation milk yield, reproductive performance, and culling in dairy cows. J Dairy Sci 2018;101:1-10. doi:10.3168/jds.2016-11714.

Neves RC, Leno BM, Curler MD, Thomas MJ, Overton TR, McArt JAA. Association diseases, culling, reproduction, and milk production in Holstein cows. J Dairy Sci 2017;100:547-5. doi:10.3168/jds.2017-13313.

Ferguson JD. Nutrition and reproduction in dairy herds. Vet Clin N Am Food Anim Pract 2005;21:325-333.

Bernabucci UL, Basiricó P, Morera D, Dipasquale A, Vitali F, Piccioli C, Calamari L. Effect of summer season on milk protein fractions in Holstein cow. J Dairy Sci 2015;98:1815-1827. doi: 10.3168/jds.2014-8788.

Collard BL, Boettcher PJ, Dekkers JCM, Petitclerc D, Schaeffer LR. Relationships between energy balance and health traits of dairy cattle in early lactation. J Dairy Sci 2000;83:2683–2690. doi: 10.3168/jds.S0022-0302(00)75162-9.

Calderon DF, Cook NB. The effect of lameness on the resting behavior and metabolic status of dairy cattle during the transition period in a free stall-housed dairy herd. J Dairy Sci 2011;94:2883-2894. doi:10.3168/jds.2010-3855.

AOAC. Association of Official Analytical Chemists. Official methods of analysis. 18th. ed. Association of Official Analytical Chemists Press. Gaithersburg, MD. AOAC International. 2006.

Goering HK, Van Soest PJ. Forage fiber analyses (apparatus, reagents, procedures, and some applications) Agricultural handbook no. 379. ARS-USDA, Washington, DC, USA. ARS-USDA Press Inc. 1970.

Publicado

15.06.2021

Cómo citar

López-Ordaz, R., Pérez-Hernández, G., Ramírez-Ramírez, H. A., López-Ordaz, R., Mendoza-Martínez, G. D., & Ruíz-Flores, A. (2021). Relationships among ß-hydroxybutyrate, calcium and non-esterified fatty acids in blood with milk yield losses at early lactation. Revista Mexicana De Ciencias Pecuarias, 12(1), 18–35. https://doi.org/10.22319/rmcp.v12i1.5105
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