Accuracy of genomic values predicted using deregressed predicted breeding values as response variables

Autores/as

  • Agustín Ruíz-Flores Posgrado en Producción Animal, Departamento de Zootecnia, Universidad Autónoma Chapingo, Carretera México-Texcoco km 38.5. Chapingo, 56230 Estado de México. México.
  • José Guadalupe García-Muñiz Posgrado en Producción Animal, Departamento de Zootecnia, Universidad Autónoma Chapingo, Carretera México-Texcoco km 38.5. Chapingo, 56230 Estado de México. México.
  • Joel Domínguez-Viveros Facultad de Zootecnia y Ecología, Universidad Autónoma de Chihuahua. Chihuahua, Chihuahua. México.
  • Rufino López-Ordaz Posgrado en Producción Animal, Departamento de Zootecnia, Universidad Autónoma Chapingo, Carretera México-Texcoco km 38.5. Chapingo, 56230 Estado de México. México.
  • Fernanda Ramírez-Flores Universidad Autónoma de Chapingo

DOI:

https://doi.org/10.22319/rmcp.v8i4.4237

Palabras clave:

Genomic evaluation, Deregressed predicted genetic value, Genomic predicted value, Accuracy, Genetic correlation.

Resumen

Highly accurate predicted genetic values must be obtained at an early age to promote rapid genetic progress. The objectives of this study were to compare accuracies (R2) of genomic values (GVs) and to estimate genetic correlation between true genetic values and genomic values obtained using predicted breeding values (EBV) and deregressed EBV (DEBV) as response variables. A first population, effective population size 800 and 100 generations, was simulated using the QMSim program to generate linkage disequilibrium. Thereafter, 20 males and 200 females were used to generate a second 14-generation population, with 6,400 individuals per generation and its corresponding phenotype and genotype in SNP terms. Generations 7 to 14 of the second population were used in several combinations as training (PEn) and evaluation (PEv) subpopulations. GVs, their accuracies, and genetic correlations were obtained using the GenSel and ASREML programs. When PEn was the largest, the mean R2 of GV was the highest, 0.77 ± 0.01. The closer PEn was to PEv, the higher the R2, and correspondingly, the lower the predicted error variance. The trends for R2 and PEV held true for both EBV and DEBV used as response variables. Genetic correlation estimates between true genetic values and GVs varied from 0.41 to 0.53 in the two scenarios studied. They decreased when PEn and PEv were farther apart. There were only slight advantages of using DEBVs as response variables over using EBVs.

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Citas

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Publicado

30.09.2017

Cómo citar

Ruíz-Flores, A., García-Muñiz, J. G., Domínguez-Viveros, J., López-Ordaz, R., & Ramírez-Flores, F. (2017). Accuracy of genomic values predicted using deregressed predicted breeding values as response variables. Revista Mexicana De Ciencias Pecuarias, 8(4), 445–451. https://doi.org/10.22319/rmcp.v8i4.4237
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